CBD - Did You Know That?

The action of CBD on neurological diseases

According to researchers at the Salk Institute in California, their 2017 study found evidence of CBD that could help remove dementia and increase connections between brain cells.

These results have been validated by other laboratories. While the US Food and Drug Administration has not yet approved a CBD drug to treat dementia, it has approved a CBD-based drug to treat epilepsy.

There are three ways CBD can work to improve the health outcomes of people with dementia: by reducing inflammation, reducing oxygen buildup, and acting as a brain stimulant and neuroprotective agent.

From the user’s perspective, CBD can reduce stress and anxiety in people with dementia, as well as reduce the decline in memory and other brain functions. 

It should be noted that there are many controversies and claims about CBD that companies have made about its positive effects. The FDA warns that CBD can cause liver damage (as shown in some experiments on very high dose animals) and can affect the metabolism of other drugs. The agency also says long-term side effects remain unknown.


Alzheimer’s disease

The topic of CBD health benefits continues to grow with new research on CBD and Alzheimer’s. In recent studies, CBD has been shown to reduce or eliminate the impact of inflammation, oxygen buildup, and brain cell decline.

Inflammation has been shown to increase the negative impact of Alzheimer’s disease. The inflammatory response occurs when the brain’s immune cells fail to eliminate disorienting blockages. Inflammation which is a major cause of Alzheimer’s symptoms can often be reduced by using CBD oil.

Oxygen is released as a stress-induced reactive component of Alzheimer’s disease. When inflammation occurs in the brain, oxygen is released as a result. The higher the inflammation, the greater the negative impact. Important brain functions, such as memory, are reduced as more oxygen is released into the brain cells.

Memory loss and other brain damage indirectly lead to an increase in oxygen to the brain. CBD is an antioxidant that helps reduce the problems associated with oxygen stress. Brain function adversely affected by oxygen stress can be improved by using CBD.

The brain cells of Alzheimer’s patients often show a rapid decline and destruction. The potential for brain tissue stimulation has recently been discovered as a potential benefit of CBD. In clinical trials, CBD has demonstrated the ability to reverse and even prevent the development of the negative impact of Alzheimer’s.

A 2011 study by Australian researchers Tim Karl and Carl Group found that CBD promotes the growth and development of brain cells, reducing the decline of memory and other brain functions


Vascular dementia

Vascular dementia is a general term that describes problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage caused by impaired blood flow to one’s brain.

For the effective treatment of vascular dementia, a 2016 study by the US National Institutes of Health (NIH) found that activating CB2 receptors (cannabinoids) in the brain helped restore better blood flow to the brain. Activation of CB2 receptors with CBD increased brain cell activity and contributed to the reduction of brain cell lesions frequently associated with vascular dementia.

Dementia with Lewy bodies

Lewy body dementia (LBD) is a disease associated with abnormal deposits of a protein called alpha-synuclein in the brain. These deposits, called Lewy bodies, affect chemicals in the brain whose changes, in turn, can lead to problems with thinking, sleep, movement, behavior and mood.

Unlike most pain, anxiety, or behavioral medications, CBD does not block acetylcholine, the main chemical that LBD attacks.

Research has shown that CBD can be an effective anti-inflammatory agent, reduces motor symptoms (tremor, stiffness, bradykinesia) and maintains circadian (sleep) rhythms.

Parkinson’s disease

Parkinson’s is a progressive chronic disease of the nervous system that mainly affects the elderly and the elderly. Parkinson’s is linked to a decrease in dopamine production and is marked by tremor, muscle stiffness and slow, inaccurate movement.

Digestive imbalance may also play a role in the progression of Parkinson’s and the severity of symptoms. Cannabinoids such as CBD have been shown to contain effective brain protectors, antioxidants and anti-inflammatory properties that may be beneficial in the management of Parkinson’s disease.

Frontotemporal dementia / Pick’s disease

Frontotemporal dementia (FTD) or frontotemporal degeneration refers to a group of disorders caused by the progressive loss of nerve cells in the frontal lobes of the brain (areas behind the forehead) or temporal lobes (regions behind the ears) that lead to symptoms of depression and psychosis.

Unlike most antipsychotic drugs, CBD does not lead to an increased risk of death. Research has shown that CBD can be an effective anti-inflammatory agent, reduces anxiety, reduces motor symptoms (tremor, stiffness, bradykinesia) and maintains circadian (sleep) rhythms.


Huntington’s disease

Huntington’s disease (HD), also known as Huntington’s chorea, is an inherited disorder that results in the death of brain cells. The oldest symptoms are often subtle problems with mood or mental abilities.

This is often followed by a general lack of coordination and insecure gait. According to 2016 research conducted by the University of Madrid, due to the effectiveness of CBD as antioxidants and its anti-inflammatory properties that are safe and tolerable at high doses, CBD can be beneficial for the management of Huntington’s disease.

Risks and side effects

The World Health Organization (WHO) stated that “no public health problems were associated with the use of pure CBD” and that there was no known association with potential for addiction or abuse, unlike most pharmaceutical alternatives.

The most commonly reported potential side effects of CBD use were diarrhea and bloating, with some also reporting nausea. About 3% of patients in the study reported liver problems and had to stop using CBD.

Specifically, in dementia, some patients have reported increased tremor with high doses of CBD. As with any new treatment, patients and caregivers need to monitor the effects and results closely.

Misconceptions and myths

1.) CBD is non-psychoactive and medicinal, while THC is recreational, not medicinal.

CBD (cannabidiol) has been shown to have antipsychotic and anti-anxiety effects in humans. This does not mean that it is non-psychoactive, but rather that the psychoactive effects are often beneficial and non-intoxicating to the “high” feelings of the THC compound (aka Tetrahydrocannabinol).

THC has also shown medicinal benefits for patients, especially for those suffering from pain or inflammation, especially when combined with CBD for patient consumption.

2.) CBD is a sedative and reduces awareness or alertness

Even in high doses (600 mg), CBD did not produce sedative effects in healthy people. CBD usually makes people feel more alert and alert, with no negative impact on sleep patterns. What is more likely to happen is that cannabis strains used by a patient who have high levels of CBD also contain a potentially sedative terpene, such as myrcene.

3.) All sources of CBD are the same

There are several sources of CBD, such as hemp, medical and isolated cannabis. Hemp-based CBD is affected by mislabeling and recent studies have found that only 31% of the 84 hemp-based CBD products tested were accurately labeled. Medical cannabis, of local origin, has consistently produced the best source of CBD, as it is maintained in stricter laboratory tests for potency and contaminants.

If you order CBD online, you know that the wrong labeling is common and you are looking for products tested by third parties, which means that independent testing has shown that the percentages declared are correct.

4.) CBD is legal in all 50 states

Despite the fact that CBD has been sold in health food stores, tobacco stores, on Amazon, etc. and legalization by many US states, the federal government has not legalized medical cannabis rich in CBD, even when there is little or no THC included.

Hemp-based CBD (with less than 0.3% THC) would not technically have this restriction, but the risks of supply and labeling are many. Officials in three states (Idaho, South Dakota and Nebraska) said they still consider hemp-based CBD illegal. Drug-based CBD has been legalized in over 30 states and is recreationally legal in a growing number of locations in the United States.

The US Federal Drug Administration recently approved a CBD drug, Epidiolex, to treat rare forms of epilepsy in patients 2 years of age and older




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